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High school seniors who use heroin commonly use multiple other drugs—and not just opioids, according to a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU Meyers College of Nursing.

The findings, published in the journal suggest that addressing heroin use among teens should take into account the probable use of multiple drugs prevalent in this population.

Heroin use has risen in the United States in connection with the ongoing opioid epidemic. Research shows a strong link between nonmedical prescription opioid use and heroin use, and suggests that these nonmedical users in particular—especially frequent users—are at high risk for using heroin.

While the relationship between opioids and heroin has been investigated extensively, fewer recent studies have examined potential links between heroin and the use of other drugs. For example, benzodiazepines—a class of depressant drugs prescribed to treat anxiety and often abused—are now commonly used with heroin and are involved in nearly a quarter (23 percent) of heroin-related overdose deaths in the United States. Indeed, nearly three out of five (59 percent) heroin-related overdose deaths involve at least one other drug.

“It may be inadequate to focus on heroin and opioid use in isolation. Considering users’ overall drug use profiles appears to be important because the concurrent use of multiple drugs can exacerbate adverse health effects associated with heroin use such as overdose,” said CDUHR researcher Joseph Palamar, PhD, MPH, the study’s lead author and an associate professor of population health at NYU School of Medicine. “A deeper understanding of how heroin users also currently use other drugs can help us to discern better prevention measures.”

Palamar and his colleagues studied a nationally representative sample of high school seniors, focusing on the 327 (of more than 92,000 studied) who reported using heroin in the past month. They examined how recent use and frequency of use of various drugs related to their current use of heroin. Students were surveyed as part of the Monitoring the Future study between 2010 and 2016.

The researchers found that high school seniors who use heroin also commonly use multiple other drugs—on average, five others. Using heroin more often was linked to an increase in using several other drugs more frequently, particularly depressants including other opioids and benzodiazepines. The frequency of concurrent use of most drugs was markedly high among those who reported using heroin 10 to 39 times in the past month.

Interestingly, this trend was reversed among students who reported the highest frequency of current heroin use. Specifically, those who reported using heroin 40 or more times in the past month actually reported less concurrent use of other drugs, both in terms of number of drugs and frequency of use. The researchers hypothesize that this drop in use of other drugs may be attributable to the increased costs and needs associated with such high levels of heroin use.

While alcohol was one of the most common drugs consumed among high school seniors who use heroin, most levels of alcohol use were associated with lower odds of frequent heroin use. This aligns with previous studies showing an inverse relationship between heroin and alcohol use.

“Our study shows that increases in the frequency of heroin use are associated with shifts in the nature and frequency of using multiple drugs. More frequent heroin use was associated with a higher percentage and frequency of opioid and benzodiazepine use, which compounds the risk of overdose,” said CDUHR researcher Pedro Mateu-Gelabert, PhD, an investigator at National Development and Research Institutes, Inc. “Prevention measures should consider these use patterns among heroin-using adolescents.”

In addition to Palamar and Mateu-Gelabert, Austin Le of NYU College of Dentistry co-authored the study. The study, “Not Just Heroin: Extensive Polysubstance Use among US High School Seniors Who Currently Use Heroin,” is published in the journal Drug and Alcohol Dependence.

Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health (K01DA038800, R01DA035146, R01DA041501, and P30DA011041). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

was originally published on the New York University website.

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Conyers had initially told the Associated Press he did not know anything about the allegations. A spokesperson for Conyers, however, said that he thought the AP reporter was asking him about recent allegations, which he didn’t know about.

On Dec. 5, Conyers Goldplated And Enamel Multistone Earrings one size Percossi Papi 4VqsouAosM
that he wouldn’t run for re-election, but again denied the allegations. “My legacy can’t be compromised or diminished in any way by what we’re going through now. This too shall pass,” Conyers said. “My legacy will continue through my children. I have a great family here, especially in my oldest boy, John Conyers III, who I endorse to replace me in my seat in Congress.”

Colorado Congresswoman Diana DeGette told MSNBC on Monday that former Congressman and San Diego Mayor Bob Filner had tried to pin her to the door of an elevator and kiss her, but she pushed him away.

Filner served in Congress from 1993 to 2012, when he became Mayor of San Diego. He resigned from the mayorship after one year amid sexual harassment allegations.

“I was trying to establish personal relationships,” studded Linda Besace bag Brown Tila March cR9BL0tbR9
“I sincerely apologize to all of you. … For the part that I have played, for putting the city through a difficult time, I apologize.”

That October, Filner pleaded guilty to to false imprisonment and battery charges that were related to the sexual harassment allegations, according to the New York Times .

Leeann Tweeden, a model, sportscaster, and radio host, described in a November 16 blog post how in 2006, Franken, who was not yet a Senator but working as a comedian, forced her to kiss him, and then groped her while she was asleep. At the time, they were on a USO tour in the Middle East, which Franken was headlining.

Franken apologized for the photograph, but said he recalled the incident differently. “I don’t know what was in my head when I took that picture, and it doesn’t matter. There’s no excuse. I look at it now and I feel disgusted with myself. It isn’t funny. It’s completely inappropriate,” he said in a lengthy statement. “While I don’t remember the rehearsal for the skit as Leeann does, I understand why we need to listen to and believe women’s experiences.” Franken also joined multiple senators calling for an ethics investigation into his conduct.

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In the weeks since Tweeden’s blog post, seven other women have come forward with similar allegations against Franken. On Dec. 6, led by a few Senate Democratic women, a total of 23 Senate Democrats called on Franken to resign. Franken announced in a Dec. 7 speech on the Senate floor that he would resign in the “coming weeks.” Franken said that some of the claims against him “are simply not true,” while others he remembers “very differently.”

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